Principal/Senior Scientist position – Preclinical Translation at Morphocell Technologies

Position: Principal/Senior Scientist – Preclinical Translation
Type: Full-time, On-site
Company: Morphocell Technologies
Location: 275 Armand-Frappier Blvd., Laval, (QC) H7V 4A7, Canada

Position Overview:

As a Principal/Senior Scientist on the Preclinical Translation team, you will play a central role in assessing the safety and efficacy of our groundbreaking treatments. Your expertise will shape the selection and development of clinically relevant disease models through execution of GLP preclinical studies. This role offers a unique opportunity to contribute to cutting-edge cell therapies while thriving in a collaborative and innovative environment.

Key responsibilities:

• Lead preclinical studies that provide scientific rationale for advancement to human trials, including safety, efficacy, and mechanism of action studies using clinically relevant in vitro and in vivo models.
• Effectively collaborate cross-functionally with process & analytical development, clinical, regulatory, and manufacturing teams to ensure seamless project progression and integration of findings.
• Manage CROs for the execution of small and large animal GLP safety studies, including protocol drafting and study management.
• Design and execute experiments that deliver quality- and data-driven decisions supporting global regulatory compliance.
• Analyze and interpret complex datasets, generate, and present reports to leadership and cross-functional teams.
• Remain current on emerging technologies, scientific approaches, and regulatory guidance.
• Mentor junior scientists and research associates, actively supporting a collaborative culture of continuous improvement, scientific rigor, respect, and trust.

Qualifications:

• Education. Ph.D. in Biological Sciences, Stem Cell Biology, Pharmacy, Biomedical Engineering or a related fields with 5+ years of preclinical development experience.
• Leadership. Demonstrated ability to lead research teams and manage multiple complex projects simultaneously, ensuring alignment with organizational goals and timelines.
• Leadership. Experience with direct supervision, mentorship, and development of a team of scientists and research staff, fostering a culture of collaboration, innovation and scientific rigor.
• Technical. Background in non-clinical study design, model development, and a range of in vivo models, ideally including liver disease models.
• Technical. Proficient in basic cell characterization techniques, including flow cytometry, ddPCR, qPCR, ELISA.
• Technical. Solid analytical and critical thinking skills with the ability to efficiently troubleshoot and solve problems, as well as proactively identify risks and propose mitigation solutions.
• Organization. Excellent written and verbal communication, with the ability to analyze complex data sets, draw scientific conclusions, and generate reports for internal and external stakeholders.
• Organization. Well organized with efficient time management skills including the ability to prioritize effectively.

Preferred Qualifications:

• Leadership. Experience in cell therapy development and CRO management.
• Technical. Familiarity with regulatory submissions and interactions with health authorities.
• Technical. Expertise cultivating and differentiating human pluripotent stem cells.

If you are a highly motivated scientist with expertise in cell therapy preclinical development and have a passion for driving innovation, we invite you to apply and be part of our mission to revolutionize patient care through cutting-edge therapies.

Please submit your resume and cover letter to: career@morphocell.com

About Morphocell Technologies:

Morphocell Technologies, based in Montreal, Quebec, is a preclinical, regenerative medicine company focused on the development and commercialization of advanced cell therapies and engineered tissues. The company is creating an extensive platform, based on allogeneic, stem cell-derived, engineered tissues, aimed at addressing severe organ deficiencies and revolutionizing organ replacement therapy. As a small, yet rapidly growing biotechnology company, Morphocell fosters a collaborative environment where a diverse group of young scientists, clinicians, and innovators come together with one shared goal: combating incurable diseases. The company has established robust international partnerships and collaborations, thriving on the rich diversity and multi-disciplinary nature of our expanding team. By joining us, you will contribute to transforming the landscape of liver disease treatment.

As a leading biotechnology company, Morphocell is driven by a deep commitment to innovation and a mission to enhance patient lives. That dedication has propelled us to the forefront of cutting-edge cell therapies for a range of diseases. As our portfolio continues to grow, we are actively seeking a highly skilled and motivated Principal/Senior Scientist to join our Preclinical Translation team.

Morphocell Technologies embraces diversity and equal opportunity. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills and provide employees with a work environment free of discrimination and harassment.