{"id":546,"date":"2019-01-13T02:12:52","date_gmt":"2019-01-13T07:12:52","guid":{"rendered":"http:\/\/mrm.research.mcgill.ca\/?page_id=546"},"modified":"2019-10-03T16:19:10","modified_gmt":"2019-10-03T20:19:10","slug":"hommage-charles-leblond","status":"publish","type":"page","link":"https:\/\/mrm.research.mcgill.ca\/fr\/hommage-charles-leblond\/","title":{"rendered":"Hommage \u00e0 Charles Leblond"},"content":{"rendered":"<p>La d\u00e9couverte des <strong>cellules souches<\/strong> de mammif\u00e8res par le <strong>Pr\u00a0Charles\u00a0Leblond<\/strong> et son \u00e9tudiant, <strong>Yves\u00a0Clermont<\/strong>, en 1953 marque l\u2019entr\u00e9e de l\u2019Universit\u00e9\u00a0McGill dans un tout nouveau domaine\u00a0: la <strong>m\u00e9decine r\u00e9g\u00e9n\u00e9rative<\/strong>. Dans un article fondateur publi\u00e9 en 1954, les chercheurs exposent pour la premi\u00e8re fois la <strong>th\u00e9orie du renouvellement des cellules souches<\/strong>: des cellules indiff\u00e9renci\u00e9es se divisent pour donner naissance \u00e0 d\u2019autres cellules indiff\u00e9renci\u00e9es, qu\u2019ils appellent \u00ab\u00a0cellules souches\u00a0\u00bb. Ils d\u00e9crivent les \u00e9tapes de la diff\u00e9renciation des spermatozo\u00efdes dans les testicules, identifient pour la premi\u00e8re fois une population de <strong>\u00ab\u00a0cellules souches\u00a0\u00bb<\/strong>, terme qu\u2019ils sont d\u2019ailleurs les premiers \u00e0 utiliser dans ce contexte de la biologie. Cette fabuleuse d\u00e9couverte a sem\u00e9 le germe de la m\u00e9decine r\u00e9g\u00e9n\u00e9rative qui r\u00e9volutionne actuellement les sciences biom\u00e9dicales. Par la suite, sa mise en application a permis au corps m\u00e9dical de mieux comprendre et de combattre de nombreuses maladies touchant l\u2019\u00eatre humain.<\/p>\n<p style=\"text-align: center;\"><a href=\"http:\/\/mrm.research.mcgill.ca\/wp-content\/uploads\/2019\/01\/tribute_charles_leblond_cell.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-542 aligncenter\" src=\"http:\/\/mrm.research.mcgill.ca\/wp-content\/uploads\/2019\/01\/tribute_charles_leblond_cell.jpg\" alt=\"\" width=\"427\" height=\"318\" srcset=\"https:\/\/mrm.research.mcgill.ca\/wp-content\/uploads\/2019\/01\/tribute_charles_leblond_cell.jpg 427w, https:\/\/mrm.research.mcgill.ca\/wp-content\/uploads\/2019\/01\/tribute_charles_leblond_cell-300x223.jpg 300w\" sizes=\"auto, (max-width: 427px) 100vw, 427px\" \/><\/a><\/p>\n<h6 style=\"text-align: center;\"><strong><u>Th\u00e9orie du renouvellement des cellules souches\u00a0\u2013 Clermont,\u00a0Y. et Leblond,\u00a0C.P. Renewal of spermatogonia in the rat testis. <em>Am\u00a0J\u00a0Anat<\/em> 1953\u00a093:\u00a0475-502<\/u><\/strong><\/h6>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\">Le Dr\u00a0Leblond a re\u00e7u de multiples distinctions et a \u00e9t\u00e9 intronis\u00e9 au <strong>Temple de la renomm\u00e9e m\u00e9dicale canadienne<\/strong>. De plus, sa \u00ab\u00a0<strong>th\u00e9orie des cellules souches<\/strong>\u00a0\u00bb lui a valu trois mises en nomination pour un <strong>prix Nobel<\/strong>. Quant au Pr\u00a0Clermont, qui a obtenu un doctorat en anatomie de l\u2019Universit\u00e9\u00a0McGill en 1953 sous la supervision du Dr\u00a0Leblond, il est devenu un pionnier de la microscopie \u00e9lectronique et a \u00e9t\u00e9 le premier \u00e0 d\u00e9crire l\u2019appareil de Golgi et \u00e0 d\u00e9finir la structure tridimensionnelle de cet organelle.<\/p>\n<p style=\"text-align: justify;\">Depuis, la <strong>m\u00e9decine r\u00e9g\u00e9n\u00e9rative<\/strong> a fait des pas de g\u00e9ant, et on s\u2019attend \u00e0 ce que d\u2019ici un quart de si\u00e8cle, la recherche dans ce domaine et les applications connexes atteignent une valeur de 100\u00a0milliards de dollars \u00e0 l\u2019\u00e9chelle mondiale.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La d\u00e9couverte des cellules souches de mammif\u00e8res par le Pr\u00a0Charles\u00a0Leblond et son \u00e9tudiant, Yves\u00a0Clermont, en&#8230;<\/p>\n","protected":false},"author":27,"featured_media":1121,"parent":0,"menu_order":23,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-546","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hommage \u00e0 Charles Leblond | MRM<\/title>\n<meta name=\"description\" content=\"La d\u00e9couverte des cellules souches de mammif\u00e8res par le Pr\u00a0Charles\u00a0Leblond et son \u00e9tudiant, Y.Clermont en 1953 marque l\u2019entr\u00e9e de l\u2019Universit\u00e9\u00a0McGill\" \/>\n<meta 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