{"id":12791,"date":"2024-10-03T12:43:33","date_gmt":"2024-10-03T16:43:33","guid":{"rendered":"https:\/\/mrm.research.mcgill.ca\/event\/gen-webinars-navigating-gmp-manufacturing-workflows-for-rna-lnp-therapeutics\/"},"modified":"2024-10-03T13:56:59","modified_gmt":"2024-10-03T17:56:59","slug":"webinaire-gen-naviguer-dans-les-flux-de-travail-de-fabrication-bpf-pour-les-therapies-a-base-de-rna-lnp","status":"publish","type":"scrm_events","link":"https:\/\/mrm.research.mcgill.ca\/fr\/event\/webinaire-gen-naviguer-dans-les-flux-de-travail-de-fabrication-bpf-pour-les-therapies-a-base-de-rna-lnp\/","title":{"rendered":"Webinaire GEN : Naviguer dans les flux de travail de fabrication BPF pour les th\u00e9rapies \u00e0 base de RNA-LNP"},"content":{"rendered":"<p>Au cours des derni\u00e8res ann\u00e9es, les nanoparticules lipidiques encapsulant l&rsquo;ARN (RNA-LNPs) ont \u00e9merg\u00e9 comme une nouvelle modalit\u00e9 th\u00e9rapeutique, avec le potentiel de changer le rythme de l&rsquo;innovation biopharmaceutique. La fabrication en conformit\u00e9 avec les bonnes pratiques de fabrication (BPF) des RNA-LNPs est \u00e0 la fois laborieuse et gourmande en ressources, n\u00e9cessitant des protocoles stricts et un contr\u00f4le environnemental rigoureux pour garantir l&rsquo;int\u00e9grit\u00e9 et la coh\u00e9rence de l&rsquo;ARN, ainsi qu&rsquo;un contr\u00f4le qualit\u00e9 et une documentation robustes. \u00c0 mesure que les RNA-LNPs \u00e9voluent et s&rsquo;\u00e9tendent \u00e0 de nouvelles applications et \u00e0 diverses \u00e9chelles, le processus de fabrication pr\u00e9sente de nouveaux d\u00e9fis que les entreprises biopharmaceutiques doivent relever pour s&rsquo;assurer que leurs flux de travail restent efficaces et productifs. Lors de ce webinaire GEN, David Sokolowski et Ingram Vargas partageront des strat\u00e9gies pour naviguer avec succ\u00e8s dans les flux de travail, processus et technologies en constante \u00e9volution pour les vaccins et th\u00e9rapies \u00e0 ARN, notamment :<\/p>\n<ul>\n<li>Aper\u00e7us des opportunit\u00e9s et des d\u00e9fis li\u00e9s \u00e0 la complexit\u00e9 et \u00e0 la diversit\u00e9 des RNA-LNPs<\/li>\n<li>Un aper\u00e7u du processus de fabrication de l&rsquo;ARN, y compris la transcription in vitro (IVT), la filtration tangentielle \u00e0 flux (TFF), et les flux de travail d&rsquo;encapsulation<\/li>\n<li>Consid\u00e9rations sur la mont\u00e9e en \u00e9chelle, l&rsquo;analyse et les installations pour rationaliser la fabrication GMP des RNA-LNPs et permettre la production \u00e0 diff\u00e9rentes \u00e9tapes du d\u00e9veloppement clinique<\/li>\n<li>Une session de questions-r\u00e9ponses en direct suivra la pr\u00e9sentation, vous offrant la possibilit\u00e9 de poser des questions \u00e0 notre panel d&rsquo;experts.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4>Intervenants<\/h4>\n<p><strong>Ingram Vargas, PhD<\/strong><br \/>\nScientifique en applications sur le terrain<br \/>\nCytiva<\/p>\n<p><strong>David Sokolowski<\/strong><br \/>\nResponsable mondial des flux de travail<br \/>\nTh\u00e9rapeutiques \u00e0 base d&rsquo;acides nucl\u00e9iques<br \/>\nCytiva<\/p>\n<p><strong>Mardi 8 Octobre 2024 \u2013 11h HE<\/strong><br \/>\n<strong>En ligne \u2013 Inscription requise<\/strong><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.genengnews.com\/multimedia\/webinars\/navigating-gmp-manufacturing-workflows-for-rna-lnp-therapeutics\/\" class=\"button more\" target=\"_blank\">Inscription<\/a>\n<p>Webinaire produit avec le soutien de :<\/p>\n<p><a href=\"https:\/\/www.precisionnanosystems.com\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"https:\/\/gennewsstg.wpengine.com\/wp-content\/uploads\/2021\/12\/PrecisionNanosysems_logo.jpg\" alt=\"Precision Nanosystems logo\" width=\"529\" height=\"111\"><\/a><\/p>\n","protected":false},"featured_media":12788,"template":"","meta":{"_acf_changed":false,"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"ngg_post_thumbnail":0},"class_list":["post-12791","scrm_events","type-scrm_events","status-publish","has-post-thumbnail","hentry","scrm_events_category-seminars-fr"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Webinaire GEN : Naviguer dans les flux de travail de fabrication BPF pour les th\u00e9rapies \u00e0 base de RNA-LNP | MRM<\/title>\n<meta name=\"description\" content=\"Webinaire GEN : Naviguer dans les flux de travail de fabrication BPF pour les th\u00e9rapies \u00e0 base de RNA-LNP. David Sokolowski et Ingram Vargas.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mrm.research.mcgill.ca\/fr\/event\/webinaire-gen-naviguer-dans-les-flux-de-travail-de-fabrication-bpf-pour-les-therapies-a-base-de-rna-lnp\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Webinaire GEN : Naviguer dans les flux de travail de fabrication BPF pour les th\u00e9rapies \u00e0 base de RNA-LNP | MRM\" \/>\n<meta property=\"og:description\" content=\"Webinaire GEN : Naviguer dans les flux de travail de fabrication BPF pour les th\u00e9rapies \u00e0 base de RNA-LNP. 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