One of the main goals of the MRM Network is to encourage research that seeks novel forward-looking insight and discovery in a basic understanding of biological concepts of stem cells, which translate into novel technologies and RM. In that sense, it is crucial that MRM supports our researchers in using the numerous quality platforms that have been built across the McGill network.

You will find here a list of MRM Affiliated Core Facilities across McGill research institutes and hospitals, including:

 

Lady Davis Institute for Medical Research

Core Facility  Description Website Contact
Flow Cytometry Facility
Provides complete flow cytometry analysis and cell sorting services in terms of experimental design, instrumentation, training, technical assistance and scientific guidance. Website Christian Young, Manager Email
High-Performance Computing
Facility
Provides expertise in structure-based drug design. Computational simulation of drug/target interactions, and identification of novel drug candidates based on the three-dimensional structure of the target. Website Jian Hui Wu, Scientific Director Email
Peptide Synthesis Laboratory
Specializes in various custom and contract services related to peptide science. Peptides are complex molecules and each peptide sequence is unique with regard to its chemical and physical properties. Website Hinyu Nedev, Manager Email
The George and Olga Minarik
Research Pathology Facility
Part of the Montreal Center for Experimental Therapeutics in Cancer (MCETC), it provides pathological and histological services to support research at the Lady Davis Institute (LDI), as well as other universities and companies. Website Naciba Benlimame, Manager
Email
Cell Imaging Facility
Provides expertise in confocal, live cell imaging and epifluorescent microscopy to the researchers of the Lady Davis Institute as well as external researchers from academic and industry. Website Chia-Hao (Jasper) Chang, Manager
Email
Cell Processing Center
Designed as an enabling infrastructure to support the prosecution of early phase clinical trials of cell-based therapies where processing of human cell and tissue is required as part of the study. Website Nicoletta Eliopoulos, Director
Email
Small Animal Research Core
The mission of the Animal Resource Centre (ARC) is to facilitate the research of scientists while ensuring the highest quality of care for the animals it houses.
It offers advice and support to the LDI, JGH, McGill, and other academic and non-academic communities.
Website TBA
NanoString Gene Expression
Profiling
The NanoString™ nCounter® Analysis System is a hybrid capture-based technology that allows for quantitative, highly multiplex gene expression analysis in minimal sample volumes without PCR artifacts. Website Email

Life Sciences Complex

Core Facility Description Website Contact
Advanced BioImaging Facility
(ABIF)
State-of-the-art light microscopy: from planning to publication, broad expertise including live cell, 3D and quantitative imaging. Website Nelly Vuillemin, Image Analyst Email
Imaging and Molecular
Biology Platform
(Pharmacology & Therapeutics)
The Platform is part of the Green Chemistry CFI initiative and a centralized resource for microscopy and molecular biology equipment. The platform provides instruments, training and assistance to internal and external researchers. Website Nicolas Audet, Manager Email
Surface Plasmon
Resonance – Mass Spectrometry
(Pharmacology & Therapeutics)
Surface plasmon resonance (SPR/BIACORE) for label-free, real-time protein interaction analysis. MALDI-TOF/TOF and ESI-qTOF systems for mass spectrometry (MS) applications including MALDI tissue imaging and ultra-high resolution LC-MS proteomics. Website Mark Hancock, Manager Email
TCP Infection and Inflammation Core
Provides standardized functional and outcome analysis for in vivo models of infectious and inflammatory diseases. Website Mitra Yousefi, Manager Email
Flow Cytometry
Innovation Platform
(GCRC)
Located in the Bellini Pavilion of the Life Sciences Complex, the Core facility provides instrumentation and technical assistance to perform laser-based flow cytometric analysis, as well as providing an operator based cell sorting service. Website Julien Leconte – Camille Stegen, Managers Email
Histology Innovation Platform
(GCRC)
The Goodman Cancer Research Centre Histology Facility provides a full range of histology services to the McGill research community as well as the surrounding academic and private sectors at very competitive prices. Website Cleber Moraes, Manager Email
Single Cell Imaging
and Mass Cytometry
Analysis Platform
(GCRC)
The Single Cell and Imaging Mass Cytometry Platform (SCIMAP) is a core facility at the GCRC housing Fluidigm CyTOF (Cytometry by Time of Flight) mass cytometry technologies for analyzing dissociated tissues and blood (Helios) and tissue sections (Imaging Mass Cytometry (IMC) – Hyperion), with dedicated, highly qualified personnel to assist with assay development and data analysis. In collaboration with Fluidigm and via in-house optimization, SCIMAP provides validated and customizable antibody panels for detecting immune cell lineage and activation status and other phenotypes, reducing optimization time and costs. Website Yuhong Wei, Manager Email
Metabolomics Innovation
Resource (MIR)
(GCRC)
The Goodman Cancer Research Centre’s metabolomics core facility, the Metabolomics Innovation Resource (MIR), consists of a large array of platforms managed by professional staff and in collaboration with the Oncometabolism research team. Website Daina Avizonis, Manager Email
McGill Integrated Core
for Animal Modeling
(GCRC)
Mouse models of human disease are an invaluable research resource in the medical research community. At the McGill Integrated Core for Animal Modeling (MICAM), we offer various services related to animal model generation and maintenance. Website Mitra Cowan, Manager Email
McGill Platform for
Cellular Perturbation
(GCRC)
The McGill Platform for Cell Perturbation (MPCP) provides all McGill researchers with low-cost and rapid access to the latest functional genetic tools for biological research. The mission of the MPCP is to support functional investigations of mammalian genomes by providing McGill researchers with complementary means of genetic perturbation that can be applied in order to understand gene function. These comprehensive technological platforms include arrayed and sequence-verified lentiviral genome-wide shRNA (gene suppression), cDNA (for gene overexpression) and CRISPR (for gene knockout/editing; human) libraries. These collections, in arrayed bacterial glycerol stocks, offer a renewable resource for diverse customized screening or testing of individual genes of interest across the human and mouse genomes. Website Geneviève Morin, Manager Email
Bioinformatics Core
Technology Platform
(GCRC)
The Canadian Centre for Computational Genomics (C3G) has partnered with the Goodman Cancer Research Centre (GCRC) to setup and operate a bioinformatics hub at the GCRC. The said hub will:
– Provide on-demand bioinformatics analysis services to participating GCRC researchers.
– Identify training needs and organize training events at the GCRC
– Offer advice and guidance on bioinformatics topics to GCRC researchers through consultations and office hours.
Website Alain Pacis, Manager Email

 

The Neuro

Core Facility Description  Website Contact
Early Drug Discovery Unit (EDDU)
We combine our capabilities with those of our partners to:

  • Use iPSCs and iPSC-derived neurons to study the molecular basis of neurological diseases
  • Develop new tools and technology in disease modelling and target engagement that will help to identify potential therapies
  • Translate newly developed assays onto an automated high-throughput platform that can be integrated with preclinical drug screens
Website NeuroEDDU Email

 

Research Institute of the McGill University Health Center

Core Facility Description  Website Contact
Cellular Therapy Laboratory
The mission of the Cellular Therapy Laboratory (CTL) is to ensure high quality services provided by and for future patients for transplantations or treatment through approved clinical research protocols. The services provided by the CTL are the supervision of products’ collection, its evaluation, processing, cryopreservation, release, thawing, distribution and long-term follow up. The manipulated products are cord blood, cord tissue, adipose tissue and human whole blood from autologous and allogeneic related and unrelated recipients. TBA Linda Peltier, Manager Email

 


 

Core Facility Description Website Contact
Biobank
Bringing together high-quality biospecimens and data to advance biomedical research Website Nick Bertos, Manager Email
Bioinformatics
Computational medicine core to enhance research and clinical applications in genomics Website Joël Lafond-Lapalme, Manager Email
Containment Level 3
A state-of-the-art, multipod facility for studies of tuberculosis, influenza and human immunodeficiency virus (HIV) Website Fiona McIntosh, Manager Email
Drug discovery
Structure-based drug design, synthesis and analytical support to discover promising new therapeutics Website Sanjoy Kumar Das, Manager Email
Histopathology
Accelerating disease research via specimen processing in order to visualize biological structures and molecules within tissues Website Fazila Chouiali, Manager Email
Immunophenotyping
Creating new research opportunities through advances in cell sorting and analytical flow cytometry Website Marie-Hélène Lacombe, Manager Email
Molecular Imaging
High-end microscopy for advanced biomedical research: from molecules to animal imaging Website Min Fu, Manager Email
Proteomics
Advanced instrumentation and workflows to identify and quantify proteins, and to detect biomolecular changes in health and disease Website Lorne Taylor, Manager Email
Small Animal Imaging Labs
A comprehensive technology suite for non-invasive imaging of animal models to create holistic pictures of diseases Website Mathieu Simard, Manager Email

 

The brochure and the list of equipment in each platform are available for download.

Download the brochure

Download the list of equipments


 

Core Facility Description  Website Contact
Human Islet Transplant Laboratory
The Human Islet Transplant Laboratory is able to offer researchers around the world with a vast selection of terminally derived pancreatic tissue. Website Marco Gasparrini, Manager Email

 

The brochure is available for download.

Download the brochure

 

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