2023 MRM Talks: Dr. Jean-François Trempe and Andrew Bayne


The MRM Network presents: the MRM Talks. Join us every fourth Thursday at noon to learn more about stem cells and regenerative medicine. The webinar series will feature leading scientists in the field, including MRM Principal Investigators and external guest speakers.

For each seminar, we will also highlight the work of one MRM Trainee, who will present alongside our guest speaker.

In this edition of the MRM Talks:

Dr. Jean-François Trempe,
Associate Professor, Department of Pharmacology and Therapeutics,
McGill University

“Mechanisms of protein turnover in Parkinson’s disease”



Andrew Bayne,
Ph.D. Candidate in the Trempe Lab,
McGill University

“Measuring protein turnover in human induced pluripotent stem cell organoids to study neurodegenerative diseases”

Thursday, January 26, 2023
12:00 – 1:00 PM


Missed the presentation? You can catch up on our Youtube Channel.


About the speakers:

Jean-Francois Trempe obtained his doctorate degree from the University of Oxford in 2007. After postdoctoral training at McGill and the Montreal Neurological Institute, he obtained a Faculty position at McGill in 2013. His goal is to elucidate the function of proteins implicated in Parkinson’s disease (PD) through 3D structure determination and proteomics studies, as well as design small molecules to modulate their activities. In collaboration with the Michael J. Fox Foundation and the SGC, his lab aims to design and characterize small-molecules activators for Parkin and PINK1. He holds a Tier 2 Canada Research Chair in Structural Pharmacology and has received the New Investigator Award from Parkinson Canada in 2014. He has published a total of 48 articles during his career (H-index 24, 2692 citations), mostly on the topics of ubiquitin and neurodegenerative diseases. His most important contribution to date is the structure determination of Parkin, published in Science in 2013, which revealed the mechanism of action of this important PD target.

Andrew Bayne is a PhD student in the lab of Jean-François Trempe at McGill University. He obtained his BSc in Pharmacology at McGill University and now his doctoral work focuses on the mechanisms of mitochondrial import and protein quality control in health and disease. Specifically, Andrew is interested in how the dysregulation of protein import and processing within mitochondria can lead to various neurodegenerative diseases.


We want to hear from you, and we welcome your suggestions for speakers!
If you are interested in hosting an invited speaker, please get in touch with us.

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